Department of Chemistry - PhD Student Seminar - C-H Functionalization for Hydrogen/Deuterium Exchange Reaction
Supporting the below United Nations Sustainable Development Goals:支持以下聯合國可持續發展目標：支持以下联合国可持续发展目标：
Student: Mr. Wenwei QIN
Department: Department of Chemistry, HKUST
Supervisor: Prof. Guocheng JIA
Abstract
The catalytic activation of C-H bonds has been in the spotlight of research for several decades. In addition to the numerous investigations on C-H functionalisation towards C-C, C-X, C-N, or C-O bond formation, hydrogen isotope exchange (HIE) for the selective installation of C-D and C-T bonds is also of appreciable practical importance. Generally, the overall process can be understood as the catalytic replacement of a C-H bond (mainly by transition metals) followed by substitution with either a carbon, halogen, oxygen, nitrogen atom, or hydrogen isotopes. Therefore, the HIE reaction can be considered as the most fundamental of all C-H functionalisation processes which is of great interest.