Department of Chemistry - PhD Student Seminar - Cell-Free Protein Synthesis as a Programmable Biological Chassis: From Protein Expression to Cell-Free Synthetic Platform
Supporting the below United Nations Sustainable Development Goals:支持以下聯合國可持續發展目標：支持以下联合国可持续发展目标：
Student: Ms. Danyu LI
Department: Department of Chemistry, HKUST
Supervisor: Prof. Hongkai WU
Co-supervisor: Prof. Bo Zheng (SZBL)
Abstract
Cell-free protein synthesis (CFPS) has evolved from a specialized in vitro protein expression method into a programmable platform for synthetic biology. By removing the constraints of living cells while preserving transcription, translation, energy regeneration, and metabolism, cell-free systems provide an open environment for engineering biological functions. This seminar introduces the biochemical principles of CFPS, summarizes advances in the last decade, and discusses applications in rapid prototyping, diagnostics, distributed biomanufacturing, metabolic engineering, and synthetic cell construction.