Guest Seminar - Designed Synthetic Protein Hydrogels with Predictable and Controllable Mechanical Properties for Biomedical Applications

3:00pm - 4:30pm
Lecture Theatre H (Lifts 27-28)

Designing synthetic protein hydrogels with tailored mechanical properties similar to naturally occurring tissues remains an enduring challenge in tissue engineering and stem cell and cancer research. Although there have been attempts to correlate the mechanical properties of protein hydrogels with the nanomechanics of individual building blocks, the correlation has been qualitative rather than quantitative. In this talk, we use single-molecule force spectroscopy, protein engineering and theoretical modeling to rationally design and regulate the macroscopic mechanical properties of hydrogels by considering the force-activated events at the molecular level. We further demonstrate the engineering of hydrogels of combined high strength, toughness, fast-recovery, and anti-fatigue properties. Finally, we show the use of designed hydrogels for various biomedical applications.

Event Format
Speakers / Performers:
Prof. Yi CAO
Nanjing University
Recommended For
Faculty and staff
PG students
Department of Chemical & Biological Engineering
Bioengineering Graduate Program

Tel: (852) 23588483 / Email:

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