Recent years have witnessed the exponential growths in the computing power and the emergence of big data in different shapes and forms. These technological advancements gave rise to more elaborate and realistic representations of the social and urban environments that currently house the majority of the population. They also contribute to the growing capability of modeling human mobility both at finer spatiotemporal scales and with wider coverages. Microsimulations as analytical tools were brought forward a few decades ago and have gained rising popularities in urban analytics following the current developments. Data-centric approaches have also received much attention in the geospatial and urban research domains. Against this backdrop, this talk will cover some of the speaker’s works in big data analytics and urban microsimulations during the past few years. Several research topics will be discussed, including urban spatial interactions, land use patterns, agent-based simulations, and future scenario analysis. The talk will end with a few remarks on some possible future research directions in urban and transportation arenas.